UVa researchers publish antibiotics study

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By The Daily Progress Staff

Published: October 1, 2008

University of Virginia and Harvard researchers recently published work on a new approach toward creating more effective antibiotics.

“As bacteria become more resistant to our current classes of antibiotics, there also has been a general lack of new targets for developing novel antibiotics,” UVa professor John Bushweller said of a new study he led, which appeared in the Sept. 26 edition of Molecular Cell.

The findings — which determined the structure of an integral membrane enzyme in cell membranes — were made with researchers from UVa and Harvard Medical School.

Determining a protein’s structure is vital in order to understand how it works and how it can be used as a drug target.

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